The New England Patriots put their 10-game win streak on the line versus the Buffalo Bills in an AFC East showdown. In Kansas City, the Chiefs aim to keep their slim playoff hopes alive versus the Los Angeles Chargers.
In the NFC, Matthew Stafford faces his former team in the Detroit Lions.
Week 15 also features a good interconference showdown between the Green Bay Packers and Denver Broncos. Denver is enjoying its own 10-game winning streak.
Who wins and who loses? USA TODAY Sports provides the early predictions for Week 15:
Odds courtesy of BetMGM.
NFL Week 15 predictions, picks
Atlanta Falcons vs. Tampa Bay Buccaneers
Date: Thursday, Dec. 11
Time: 8:15 p.m. ET
Location: Raymond James Stadium, Tampa, FL
TV: N/A
Streaming: Prime Video
Spread: Bucs (-5.5)
Tyler Dragon, USA TODAY: Bucs 28, Falcons 14
The Bucs had an inexplicable loss to the lowly Saints. Tampa Bay bounces back at home on a short week.
Cleveland Browns vs. Chicago Bears
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: Soldier Field, Chicago
TV: FOX
Streaming: FUBO
Spread: Bears (-7.5)
Tyler Dragon, USA TODAY: Bears 24, Browns 16
Hard to imagine the Bears losing at home to the rebuilding Browns. Myles Garrett is closing in on the NFL’s single-season sack record. The Browns win when they allow fewer than 17 points. Cleveland’s defense won’t be able to keep Chicago’s offense under 17.
Baltimore Ravens vs. Cincinnati Bengals
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: Paycor Stadium, Cincinnati
TV: CBS
Streaming: FUBO
Spread: Ravens (-2.5)
Tyler Dragon, USA TODAY: Ravens 30, Bengals 26
Both teams are coming off a loss. The Ravens have lost two straight games, including a Thanksgiving defeat to Cincy. This is pretty much a must-win game for Baltimore if they want to keep their playoff hopes alive.
Los Angeles Chargers vs. Kansas City Chiefs
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: GEHA Field at Arrowhead Stadium, Kansas City, MO
TV: CBS
Streaming: FUBO
Spread: Chiefs (-4.5)
Tyler Dragon, USA TODAY: Chiefs 26, Chargers 23
The Chargers beat the Chiefs Week 1 in Brazil. The Chiefs return the favor at home on American soil. Kansas City keeps its very slim playoff hopes alive.
Buffalo Bills vs. New England Patriots
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: Gillette Stadium, Foxborough, MA
TV: CBS
Streaming: FUBO
Spread: Bills (-1.5)
Tyler Dragon, USA TODAY: Bills 28, Patriots 24
The best two teams in the AFC East. New England’s Week 5 victory in Buffalo was Drake Maye’s coming out party. The Patriots will be rested coming off a bye, but their 10-game win streak ends at the hands of the Bills.
Washington Commanders vs. New York Giants
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: MetLife Stadium, East Rutherford, NJ
TV: FOX
Streaming: FUBO
Spread: Giants (-1.5)
Tyler Dragon, USA TODAY: Commanders 20, Giants 19
The Commanders got throttled in Jayden Daniels’ return, but the QB didn’t look healthy in Week 14. Daniels shouldn’t play another down with Washington being eliminated for postseason contention. Marcus Mariota is a capable backup.
Las Vegas Raiders vs. Philadelphia Eagles
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: Lincoln Financial Field, Philadelphia
TV: FOX
Streaming: FUBO
Spread: Eagles (-13.5)
Tyler Dragon, USA TODAY: Eagles 30, Raiders 15
Two teams at opposite ends of the spectrum. The Raiders are eliminated from the playoffs and haven’t won a game since October. The Eagles are trying to be the top seed in the NFC.
New York Jets vs. Jacksonville Jaguars
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: EverBank Stadium, Jacksonville, FL
TV: CBS
Streaming: FUBO
Spread: Jaguars (-12.5)
Tyler Dragon, USA TODAY: Jaguars 26, Jets 16
Jacksonville’s won four in a row. The Jets just extended their dubious record to 15 years without a playoff appearance, the longest active drought of all four major American sports.
Arizona Cardinals vs. Houston Texans
Date: Sunday, Dec. 14
Time: 1 p.m. ET
Location: NRG Stadium, Houston
TV: FOX
Streaming: FUBO
Spread: Texans (-7)
Tyler Dragon, USA TODAY: Texans 27, Cardinals 13
Houston’s defense just contained Patrick Mahomes and the Chiefs. Will Anderson Jr., Danielle Hunter, Derek Stingley Jr. and the Texans defense are going to give Arizona fits. Plus, C.J. Stroud should have his way versus the Cardinals offense.
Green Bay Packers vs. Denver Broncos
Date: Sunday, Dec. 14
Time: 4:25 p.m. ET
Location: Empower Field at Mile High, Denver
TV: CBS
Streaming: FUBO
Spread: Packers (-2.5)
Tyler Dragon, USA TODAY: Packers 24, Broncos 20
The Broncos have won 10 straight games. Nine of Denver’s wins have come within one score. They lose a one-score game this week against Jordan Love and the surging Packers.
Detroit Lions vs. Los Angeles Rams
Date: Sunday, Dec. 14
Time: 4:25 p.m. ET
Location: SoFi Stadium, Inglewood, CA
TV: FOX
Streaming: FUBO
Spread: Rams (-5.5)
Tyler Dragon, USA TODAY: Rams 27, Lions 24
Matthew Stafford gets revenge over his former team in LA. The Lions defense won’t be able to stop a potent Rams offense. The season-ending Achilles injury to defensive back Brian Branch is a huge blow to Detroit’s defense.
Carolina Panthers vs. New Orleans Saints
Date: Sunday, Dec. 14
Time: 4:25 p.m. ET
Location: Caesars Superdome, New Orleans
TV: FOX
Streaming: FUBO
Spread: Panthers (-2.5)
Tyler Dragon, USA TODAY: Panthers 26, Saints 20
The Saints got their biggest win of the season last week against Tampa Bay. There are good vibes in Carolina right now as the Panthers are tied for first in the NFC South. This is a trap game for the Panthers as they have two games versus Tampa Bay and a contest against Seattle to close the season. However, the Panthers get the victory in the Big Easy.
Tennessee Titans vs. San Francisco 49ers
Date: Sunday, Dec. 14
Time: 4:25 p.m. ET
Location: Levi’s Stadium, Santa Clara, CA
TV: FOX
Streaming: FUBO
Spread: 49ers (-12.5)
Tyler Dragon, USA TODAY: 49ers 25, Titans 17
The Titans scored a season-high 31 points against a stingy Cleveland defense last week. Tony Pollard rushed for 161 yards and two touchdowns. But the 49ers will contain Tennessee. San Francisco’s won three straight games and will make it four in a row.
Indianapolis Colts vs. Seattle Seahawks
Date: Sunday, Dec. 14
Time: 4:25 p.m. ET
Location: Lumen Field, Seattle
TV: CBS
Streaming: FUBO
Spread: Seahawks (-10.5)
Tyler Dragon, USA TODAY: Seahawks 26, Colts 16
Daniel Jones’ season-ending Achilles injury is a devastating blow to Indy. I don’t believe the Colts win another game this year.
Minnesota Vikings vs. Dallas Cowboys
Date: Sunday, Dec. 14
Time: 8:20 p.m. ET
Location: AT&T Stadium, Arlington, TX
TV: NBC
Streaming: Peacock
Spread: Cowboys (-6)
Tyler Dragon, USA TODAY: Cowboys 28, Vikings 20
J.J. McCarthy is coming off the best game of his young career. However, McCarthy and the Vikings offense won’t be able to keep pace with a high-powered Cowboys offense.
Miami Dolphins vs. Pittsburgh Steelers
Date: Monday, Dec. 15
Time: 8:15 p.m. ET
Location: Acrisure Stadium, Pittsburgh
TV: ESPN
Streaming: FUBO
Spread: Steelers (-3.5)
Tyler Dragon, USA TODAY: Steelers 26, Dolphins 20
The demise of Mike Tomlin in Pittsburgh was unwarranted and overblown. The Steelers are fresh off a huge win against Baltimore. Pittsburgh controls its own destiny in the AFC North. The Steelers end Miami’s four-game winning streak.
Follow USA TODAY Sports’ Tyler Dragon on X @TheTylerDragon.
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